Monday, May 16, 2011

Know More About Sanchi

Traditional Chinese Medicine, or TCM, as it was first called in the 1950s, is a compilation of several practices, theories and treatments that have been part of Chinese culture dating to as early as 2698 B.C. Although largely unexplored by consumers and practitioners of Western medicine, TCM sales account for more than half of China’s over-the-counter pharmaceutical sales. In 2005, the OTC market generated $5.2 billion in sales in China—39% of the country’s total domestic pharmaceutical revenues. [i]

The purpose of this paper, then, is to describe the origin and history of a specific TCM herb, Sanchi, its natural cultivation requirements and native habitat, medicinal uses and treatment areas, features, current delivery mechanisms and market characteristics. This is intended to be a suitable introduction to the many medical uses and scientific properties of Sanchi for readers who find themselves more familiar with Western medicine.

I. Introduction to Sanchi

Sanchi, one of the more rare Chinese medicinal herbs, is in the genus panax of the araliaceae family. [ii] Sanchi has a similar shape to ginseng. Each tuberous root contains three branches, which in turn has seven leaves; thus, “Sanchi” (In Chinese, San is three while Chi is seven) earned its name.

Sanchi contains ingredients such as saponins, polysaccharides and amino acids, which help to cure hematological diseases. Saponins help form the waxy, protective coating around plants and are believed to be useful for controlling cholesterol. [iii] The aromatic oil in Sanchi’s flowers and fruit can be extracted to produce cosmetics, and the plant may be ground into powder that is then ingested, either directly or in capsules, pills or tablets. Sanchi can be used to improve blood circulation, to stop bleeding, to reduce fat and sugar in the bloodstream, to eliminate inflammation, to reduce pain, to remove dead cells and to help new cells to grow. Sanchi is unique and rare, as it serves many functions and covers a wide range of hematological diseases. [iv]

A. Natural cultivation requirements and native habitat

The cultivation of Sanchi requires proper soil, temperature, transmittance and water quality. The herb requires well-drained, loose, moist soil, generally deep (12 inches), with a high organic content and a pH level near 5.5, which is roughly the acidity of rainwater. The ratio of shade to light should be in the range of 70%-80%. Sanchi thrives in a climate with 40 to 50 inches of annual precipitation, and it requires several weeks of cold temperatures for adequate dormancy. [v] The average annual ambient temperature should be 20-25°C (68-77°F), and the temperature range should be less than 10°C. There are more than 40 discovered micro-metal elements in suitable soil, and the concentration rate is several times higher than that of other soils, especially for iridium, germanium and nickel. These micro-metal elements stimulate the growth of unique active components in Sanchi, which differentiates Sanchi from other medicinal herbs.

According to the Codex of People’s Republic of China, Sanchi grows in the border areas of Yunnan and Guangxi provinces. From assessment and sampling results during the past several years: “The most suitable land for growing Sanchi is an eggplant-shaped region, 300 km in length, 50 km in width, between 1,000 and 1,200 meters above sea level.” The core growing area is comprised of Wenshan County and Yanshan County in Yunnan Province, together with Jingxi County and Debao County in Guangxi Province. The area of natural habitat that is suitable for cultivation is no more than 2,000 km2, and the plant must be cultivated for at least three years, under careful protection from bad weather, insects and human damage, before it may be harvested. Therefore, because this plant is difficult to grow and has a limited habitat, Sanchi can carry a higher price than other medicinal herbs. Accelerated economic development during the past two decades has generally reduced the area of cultivatable land in the plant’s core habitat. The governments in these areas have perceived the severity of the potential problem, and they have taken actions to ensure a more supportive environment for Sanchi’s development.

B. History of Sanchi

Both domestic and overseas botanists have found that Sanchi is one of the paleozoic plants, which can be traced to 750 million years ago. In 1576, Sanchi’s use as a medicinal herb was first described in Li Shi-Zhen’s Ben Cao Gang Mu (Herbalist Manual). Thereafter, Sanchi’s use was recorded in Ben Cao Gang Mu Shi Yi by Zhao Xue-Min, a scholar during the Qing Dynasty (1644-1911), and also further developed in Yi Lin Zuan Yao, Wei Yao Tiao Bian, Lin Nan Cai Yao Lu and Ri Hua Zi Ben Cao, books or articles by physicians during the late Qing Dynasty and the early Republican period (1912-1949). Today, Sanchi is taken in various forms, including capsules, infusions and tablets. Sanchi powder is typically sold in drug stores, herbal shops and specialty stores, and it may be consumed internally or applied to the skin as a poultice.

II. Scientific Components, Medicinal Uses and Treatment Areas

A. Medicinal Uses

Sanchi has several effects, including the cessation of bleeding, improved blood circulation and reduced blood stasis, or artery blockage. It is applied to heal wounds caused by animals and insect bites. In addition, Sanchi can be used to treat ulcers, as it helps to eliminate inflammation, to reduce pain, to remove dead cells and to help new ones grow. Scientific research has shown that Sanchi has antioxidant activity, which supports circulatory system disorders such as angina, dizziness and regulating blood pressure. Modern pharmaceutical studies show that Sanchi has a significant effect in reducing blood fat and glucose, and it can be used extensively to cure cardiovascular and cerebrovascular diseases, such as high blood pressure, angina and dizziness, hyperglycemia, and other diseases caused by blood stasis and thrombosis, or clotting in blood vessels. [vi]

B. Scientific Components

Sanchi contains more than 10 effective components; each component presents itself differently from the others because of its specific chemical structure. During the last 30 years, a number of chemical, pharmacological and clinical studies have demonstrated that:
  1. The major elements in the total saponins include panaxadiol, panaxatriol, and monomer saponins. [vii] Panaxadiol has the same chemical structure as ginseng. These saponins perform several functions, including: elimination of inflammation and reduction of pain; supplements for blood; reduction of blood fat, cholesterol and low-density lipoprotein; and expansion of blood vessels to improve the human body’s cardiovascular and cerebrovascular consumption of oxygen. This is widely used to cure cardiovascular and cerebrovascular diseases and other diseases that result from clotting. In China, Sanchi is often given to heart patients instead of nitroglycerin. [viii] Other saponins help remove dead cells and promote the growth of new cells; these are useful in the treatment of wounds and ulcers.
  2. Up to 8% of Sanchi’s total mass is comprised of such monosaccharides as arabinose, xylopyranose, rhamnose and other low sugars. These monosaccharides help to reduce the generation of free radicals, which can strengthen the immune system and inhibit the growth of cancer cells. [ix] The polysaccharides contained in Sanchi can improve the blood sugar levels of hyperglycemia patients and prevent such diseases from worsening.
  3. Sanchi contains eight amino acids, which can aid in blood coagulation. Among these, dencichine hemostat serves as the active element. Pharmacological studies prove that: dencichine hemostat has the same medical effect as naturally occurring batroxobin when used in equal doses. Batroxobin is extracted from snake venom and is among the most prescribed anti-bleeding agents; however, it poses production cost and safety concerns. [x] The production cost of dencichine hemostat is just one-fifth of that of batroxobin.
  4. The flavonoids and volatile oils in Sanchi contain active elements to stimulate nerves and stop cancer cell growth. More studies are being conducted on these properties.
C. Side Effects

Sanchi is most frequently associated with increased nervousness and excitement. Some reports also note vaginal bleeding. Because of its reported hypoglycemic effect, patients who must control their blood sugar levels or who have high blood pressure are advised to avoid its use.

III. Market Characteristics

A. Diseases

As discussed above, Sanchi-based medicines are mainly used to cure hematological diseases. The addressable markets for these diseases are:

1. Cardiovascular and cerebrovascular diseases and hyperlipidemic diseases

Statins are the predominant international treatment for these diseases. Commonly sold under generic names such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin, statins have annual sales of about $25 billion as a whole, while the Chinese market is estimated at roughly 12 percent, or sales of $3 billion annually. However, statins have significant, toxic side effects, such as the myositis (inflammation of skeletal muscles), myopathy (resulting in muscular weakness) and, on rare occasions, rhabdomyolysis (the pathological breakdown of skeletal muscle), which may lead to acute renal failure when products damage the kidneys. [xi] [xii] [xiii] Assuming a 10% market share for Sanchi-based medicines, global sales could reach $2.5 billion, with sales in China of about $300 million per year.

2. Kidney and liver diseases

These are listed as the fourth-most-frequent diseases internationally. The medical demand related to kidney and liver diseases in China is about $1.6 billion, while world consumption is five times as great—up to $8 billion. Traditional chemical medicines are not advantageous in this field because of the complexity inherent in these diseases. However, Chinese medicines are considered less toxic to the body and a suitable treatment alternative. Given the high-quality dosages and right marketing methods, a 20% market share is estimated. Sanchi-based medicines would contribute as much as $1.6 billion to global sales and $320 million to sales in China.

3. Wounds

Treatments for wounds and wound-related diseases need to address applications in clotting, coaptation, disinfection, healing and plastic surgery. Injured patients can include athletes, laborers, soldiers, traffic accident victims, and others who suffer during natural disasters or from the side effects of medical surgery. In China alone, there are 30 million cases per year on average, with an incidence rate of 2.6%.

B. Global Demand and Production

Currently, annual sales of Sanchi powders total more than $300 million worldwide. Largely because of production improvements, well-classified dosage management and lower production costs, global Sanchi sales are forecast to increase to $1 billion per annum, a 20% share of the global antibiotic and antiseptic market. Before the opening and reform in China, the available suitable land for Sanchi was less than approximately 6.67 million sq. m., but it has been increased to approximately 80 million sq. m. Production output has increased, as well, from less than 200 metric tons to more than 2,800 metric tons. Sanchi business revenues in Yunnan Province have increased to (RMB) 3.6 billion from less than (RMB) 200 million since 1980, an annual growth rate of 11.8%. However, Sanchi medicine revenues currently comprise less than 1% of overall Chinese medicine revenues.

IV. Conclusions

In summary, Sanchi is a medicinal herb with a wide array of applications, well-documented results and considerable market potential. Because of its limited habitat, Sanchi is particularly rare. Sanchi has been strategically chosen as a medicinal herb for deep development and comprehensive use with modern techniques of active element extraction, based on confirmed pharmacological and clinical studies. Sanchi powders already generate global sales of $300 million annually, and that figure is expected to increase substantially as production capacity accelerates to meet demand for the treatment of numerous diseases and ailments, including kidney and liver diseases, high blood pressure and loss of blood caused by external injuries.

Bibliography:
  1. BioSpectrum Bureau. May 2007. http://www.biospectrumasia.com/content/020507CHN3514.asp
  2. Chinese Herbal Medicine: Materia Medica, Third Edition by Dan Bensky, Steven Clavey, Erich Stoger, and Andrew Gamble (Sep 2004).
  3. http://en.wikipedia.org/wiki/Saponins
  4. Pharmacotherapy 2001 Jul (70):773-7.
  5. http://www.healthfoodsworld.com/store/catalog/product_info.php?products_id=97
  6. http://www.herbalremedies.com/pseudoginseng-information.html#2
  7. Effects of notoginosides on proliferation and upregulation of GR nuclear transcription factor in hematopoietic cells. Acta Pharmacologica Sinica 2007 May; 28 (5): 703-711.
  8. http://www.ppcherbs.com.au/data/herb_details.aspx?ID=101
  9. Update from Asia: Asian Studies on Cancer Chemoprevention. Annals of the New York Academy of Sciences 889:157-192 (1999) New York Academy of Sciences.
  10. http://www.sinobiomed.com/clinical_trials.htm
  11. Ghirlanda G, Oradei A, Manto A, Lippa S, Uccioli L, Caputo S, Greco A, Littarru G (1993). “Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study”. J Clin Pharmacol 33 (3): 226-9.
  12. Marcoff L, Thompson PD (2007). “The role of coenzyme Q10 in statin-associated myopathy: a systematic review”. J. Am. Coll. Cardiol. 49 (23): 2231-7. DOI:10.1016/j.jacc.2007.02.049.
  13. Graham DJ, Staffa JA, Shatin D, Andrade SE, Schech SD, La Grenade L, Gurwitz JH, Chan KA, Goodman MJ, Platt R. Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs. JAMA 2004;292:2585-90.

Opticare

Lutein is concentrated in the retinas of your eye and is necessary for good vision. Lutein is a yellow or orange pigment found in some fruits and vegetables. A diet rich in lutein may lower your risk of developing cataracts and macular degeneration.

Age-related macular degeneration (AMD) is a leading cause of vision loss in Americans 60 years and older. It is a disease that destroys your sharp central vision. You need central vision to see objects clearly and to do tasks such as reading and driving.

Lutein may also help prevent or slow down atherosclerosis, the thickening of arteries, which is a major risk for cardiovascular disease.

Where To Find Lutein:
Carrots, squash and other orange and yellow fruits and vegetables are sources of lutein. Lutein is also available as a dietary supplement. The Age Related Eye Disease (ARED) study found that high doses of lutein combined with other antioxidants helps to slow down the progression of macular degeneration.


Vitamin C in cataract development, as we age, the large concentration of ascorbic acid in the optic lens begins to decline. At the same time, the risk of developing a cataract increases, in part from oxidative damage to the lens protein. As an antioxidant, vitamin C can defend the lens by hindering the destructive process of lipid photoperoxidation, which clouds the vision. In one national study of nutrition and disease, a reduced risk of age-related macular degeneration was related to the frequency of consumption of fruits and vegetables rich in vitamin A and C.

Zeaxanthin protects the eyes from UV damage and prevents free radical damage to the retina and the lens of the eyes that is associated with diabetic retinopathy, cataract and glaucoma. 

Bilberry Extract source of anthocyanoside a powerful antioxidant for eyes and night vision and enhances microcirculation in the body. Long term use of bilberry extract helps improve nearsightedness and visual acuity. It assists the retina (the light-sensitive part of the eyes) in adjusting quickly to both darkness and light. 

Beta Carotene the red orange pigment in plants and fruits. Beta carotene is converted in the body into vitamin A which is necessary for healthy eyes and skin. 

The benefits of taking Opticare: 
  1. Improvement of eyesight
  2. Strengthening of eye muscles
  3. Better and sharper vision
  4. Read without glasses after some time
  5. Can reduce the need for wearing spectacles
A dietary supplement for:
  1. Those who wear eyeglasses or contact lenses
  2. Those who have blurry eyesight
  3. Those who need or had cataract surgical treatment
  4. Those who have poor vision when driving
  5. Those who have partial lost of eyesight
  6. Those who are always in front of the computer screen


    Testimonials from people using OPTICARE

    PRABHA (Above 50 years old)
    I have been using the product for a week. One of my eyes, which were close to being blind. My doctor has advised me to go for surgery, immediately… If not I may lose my eyesight permanently. After taking OPTICARE this eye is beginning to show vision. I can see objects with this eye already, although it is only one week since I started using the product. Also, for the past month, I am not able to read any written documents to a certain degree. This is amazing. I am confident, soon I can read fully well in any document. I can also see objects or person more clearly and sharper with my other eye. I am so grateful to OPTICARE.

    LETCHEMY (Above 50 years old)
    I am using OPTICARE FOOD SUPPLEMENT for less than a week. I normally wear eyeglasses all the time. I am still using eyeglasses, but everything seems to be BRIGHTER and SHARPER. The TV screen colors are much more beautiful. I tried to use my eyes without eyeglasses. Now I can see objects without eyeglasses, whereas, before I cannot see anything clearly unless I wear my eyeglasses. I am confident that soon I can see clearly without eyeglasses. Now I can do my cooking without eyeglasses, whereas before it was impossible to do so. Thank you OPTICARE.

    VINCENT (Above 60 years old)
    I wear reading glasses. I am using OPTICARE FOOD SUPPLEMENT for less than a week. Now I can read SMS from my phone without glasses. I can read newspapers (about 50% clarity) without glasses. Before I can only read the HEADLINES. I needed glasses to read the subject of the news. I can see people faces clearly without glasses. TV color is much sharper and brighter.

    Dreamy Rose Collagen Drink

    Dreamy Rose Marine Collagen is the collagen you can trust from wild caught deep sea fish free from environmental pollutants. It is designed as a liquid bioavailable dietary supplement to support our skin, nail and hair health, improve physiological function of our organs, helps support our cartilage and joint function and helps in wound repair. The only collagen our body recognize, contains the 20 amino acids essential for collagen synthesis combined with mixed CoQ10, Vitamin B’s, Vitamin C, folic acid, honey and lemon extract.

    It plumps up the skin, reduce fine lines, wrinkles and cellulites. It improves skin elasticity, firmness, tone and radiance. Take Dreamy Rose everyday and feel the revitalizing effects and glow of youthful skin and body.

    Dreamy Rose Collagen Drink
    • A biotechnology marine collagen, is hydrolyzed to be quickly absorbed by the body penetrate deeply into the skin from head to toe
    • It increases energy and boosts immunity
    • Relieves aching joint that are subjected to continuous wear and tear, activates ligaments and bones and treat arthritis. The body requires sufficient quantities of collagen to maintain natural rebuilding function
    • It improves sleep
    • Protects skin and maintains elasticity of skin
    • It firms up skin and over-all toning for a youthful appearance and sense of well-being
    • Strengthens bone to avoid it from becoming porous and fragile, the skin, tendons, nails, teeth and other tissues
    • Enhances eyesight with clear cornea
    • Promotes linkage of muscle cells for better elasticity
    • Protects and enhances functions of internal organs
    • Inhibit cancer cells
    Sorbitol
    • Provides bulk and sweetness with a clean, cool and pleasant taste
    • Provides one-third fewer calories than sugar – about 2.6 calories per gram
    • Is an excellent humectants, texturizing and anti-crystallizing agent
    • Does not contribute to the formation of dental caries
    • May be useful as an alternative to sugar for people with diabetes on the advice of their health care providers
    Honey Extract
    The principle constituents of honey are the simple sugars fructose and glucose. Other ingredients include water, pollen, organic acids, enzymes and various proteins. Honey nutrition is a simple, healthy and convenient way to taste sweetness.
    • Helps restore energy
    • Has a general calming effect
    • Helps dissolve mucus from coughs and colds
    • Applied externally to the skin to disinfect and heal minor wounds
    • Help maintain fitness—the glucose and fructose in honey have been predigested by the bees that produced it. These simple sugars are quickly and easily absorbed in the human digestive tract and they have an overall soothing effect.
    Coenzyme Q10
    • Coenzyme Q10 is a coenzyme that is needed by every cell in the body to produce energy. It serves its energy enhancing function by acting in the portion of the cell known as the mitochondria, often referred to as the powerhouse of the cell. Here, it aids in the production of ATP, the most important form of energy needed to drive cell reactions and keep the body running at peak capacity.
    • It has antioxidant and immune enhancing properties
    • It promotes healthy heart, brain, eyes, blood sugar level and blood pressure
    Vitamin C
    An important nutrient in the blood, skin, nervous system, teeth, bones and glands that:
    • Protects the DNA of the cells from damages caused by free radicals and mutagens
    • Has collagen-forming property
    • Contributes to the maintenance of healthy bones
    • Prevents periodontal disease
    • Faster healing of wound
    • Enhances body’s resistance to infectious disorders
    • Enhances body’s resistance to many types of cancer
    • Strengthens and protects the immune system by stimulating the activity of antibodies and immune system cells
    • Prevents or reverse the plaque formation caused by a high-cholesterol diet. The fatty plaques that form in blood vessels or atherosclerosis, are a major contributor to heart disease, Vitamin C may prevent this plaque formation by inhibiting the oxidative modification of low density lipoproteins (LDLs).
    Lemon Extract
    Freshly squeezed lemon juice has lots of health benefits:
    • Works by speeding up skin renewal and uncovering a fresh new layer of skin
    • Reduces wrinkles and treat blemishes
    • Relieves headache and cools the body
    • Has been used for many years in gout and rheumatism. Lemon juice is a diuretic that gives relief in kidney and bladder disorders.
    • Has been used in destroying intestinal worms
    • Prevents vomiting and helps to cure hepatitis and other innumerable diseases
    • Contains valuable citric acid and has more potassium than apple or grapes, which is beneficial to the heart
    • Fights and destroys the germs and bacteria
    • Cleans the toxins out of our bodies. Your skin can’t look healthy if your body is holding onto toxins! When you get rid of toxic waste in your system, your skin will be the first thing YOU notice because it looks clear, not pale and free from acne.
    Calcium D-Panthothenate (Vitamin B5)
    • Improves and increases the moisture-retention capacity of the skin (has mosturizing effect), dry skin stays supple and elastic
    • Anti-inflammatory and anti-itching effect
    • Stimulates epithelization (skin regeneration) and healing of small wounds, scratches and blisters
    • Improves the condition of damaged hair, reduces hair-splitting, makes hair easier to comb, thickens the hair and improves color and luster
    • Panthenol greatly increases the water retention capacity of the fingernails, thus increasing their flexibility and stability
    • It is the component of coenzyme A
    • It can adjust the metabolization of protein, carbohydrate and fat, fat’s synthesization and decompounds
    • Protects the skin, the mucous membrane and the body against diseases
    Fructose
    It is known as fruit sugar, the sweetest sugar in nature. Natural constituent of many fruits and vegetables.

    Citric Acid
    It bonds easily with to minerals and metals called chelation. The body can easily digest chelated minerals.

    Vitamin B Complex
    It comprises the essential B vitamin—water soluble and any excess is excreted in the urine. Only the Vitamin B12 can be stored in the body.
    • Energy Production. Vitamin B1 helps converts carbohydrates into glucose. Vitamins B2, B3, B5 and biotin convert glucose into energy up to the cellular level.
    • Health Nervous System. Vitamin B5 is needed for the correct functioning of the adrenal glands, hormone productions and nerve regulating substances. Vitamins B1, B6 and B12 are essential for the regulation, correct functioning of the entire nervous system and brain function and helps prevent the feeling of stressed, anxiety and depression.
    • Good Digestion. Vitamins B1, B2, B3 and B6 are vital for good digestion and production of hydrochloric acid. They assist in the breakdown of fats, proteins and carbohydrates.
    • Healthy Skin, Hair and Nails. Vitamins B1, B2, B3, B5, B9, B12, biotin and choline are essential for correct DNA and RNA synthesis and cell production. To ensure good health and structure of growing hair and nails and regeneration of skin to reduce drying and graying of skin, dermatitis, wrinkles, acne, rashes, falling hair and weak splitting nails.
    Folic Acid
    • Known as the “Great Protector”
    • Needed for the overall synthesis, repair and protection of DNA
    • Controls homocysteine level to decrease the risk of heart disease
    • Decreases the risk of recurrent neural tube defects in babies if taken on the first trimester of pregnancy
    • Produces white blood cells for body’s defenses
    • Prevents the shrinking of thymus gland and lymph nodes
    • Key to attaining balanced brain chemistry and accurate functioning of neurotransmitter nutrients
    • Has a powerful antidepressant effect on the brain
    • Prevents mutation of cancer cells. Cancer is a disease in which DNA has “freaked out”
    • Uses to treat gout problems
    • Recommended for people suffering with Crohn’s or Inflammatory Bowel Disease
    • Helps prevent cervical dysplasia
    • Prevents anemia – produces enough red blood cells in proper shape and assists in building new cells fast
    • Improves hearing ability
    L-Glutathione
    Essentially, it is time to supplement your diet with Marine Collagen drink and now with L-glutathione which is responsible in maintaining healthy antioxidants in the body, activating enzymes, carbohydrates metabolism, strengthening the immune system, reduce the chances of developing cancer, protect us against heart disease, slows down the aging process and for stimulation CD8 cells, which play a role in the health and growth of the body’s tissues.

    Although L-glutathione is readily made by the body, it diminishes as we age too. L-glutathione and its precursors, cysteine, glycine and L-glutamic acid increase our body’s overall level of protection. Our body makes use of it as our defense against hazards that cause us to grow sick and old. It protects our cells by attacking the external poisons and free radicals and destroys them before they have a chance to attack the cells. It is a key player in the detoxification and regeneration of our liver and combats cirrhosis and hepatitis. The side effects of chemotherapy and the growth of cataracts can be reduced with supplementation of L-glutathione. Combined with the nutrients from Dreamy Rose Marine Collagen naturally helps raise blood levels of L-glutathione. L-glutathione is a good nutritional supplement by bodybuilders and athletes who want to enhance performance and improve their health.

    Dreamy Rose Collagen Plus

    Marine collagen is known as the best source of 100% natural collagen for human skin from deep sea fish. Collagen in the body is the principal structure simple protein fiber that holds the skin together; it replenishes connective tissues that support skin structure and an important building block for healthy skin, tendons, bones and other connective tissues. Collagen is rich in four amino acid: lysine, proline, hydroxylysine and hydroxyproline. It makes up 75% of our skin. When we exceed the age of 25, our skin starts to lose collagen with appearance of aging signs such as wrinkles, sagging skin and spots by age 35 to 40. Collagen Type I (found in tendons, bones, skin, nails and other tissues) and Collagen Type III (common in fast growing tissue such as wound repair).


    Taking Dreamy Rose marine collagen plus Vitamin C + Coenzyme Q10 dietary capsule with biotechnology marine collagen is hydrolyzed to be quickly absorbed by the body and penetrate deeply into the skin from head to toe. It increases energy, relieves joint problems. Human joints are subject to continuous wear and tear, the body requires sufficient quantities of collagen to maintain natural rebuilding function. It improves sleep, firms up skin and overall toning for a youthful appearance and sense of well-being. It strengthens nails and teeth.

    Vitamin C is an important nutrient in the blood, skin, nervous system, teeth, bones and glands. Vitamin C protects the DNA of the cells from the damage caused by free radicals and mutagens. The skin, teeth and bones also benefit from vitamin C’s collagen-forming and invader-resisting properties; this vitamin contributes to the maintenance of healthy bones, the prevention of periodontal disease and the healing of wound, enhances body’s resistance to infectious disorders and many types of cancer. It strengthens and protects the immune system by stimulating the activity of antibodies and immune system cells. Vitamin C can present or reverse the plaque formation caused by a high-cholesterol diet. The fatty plaques that form in blood vessels, called atherosclerosis, are a major contributor to heart disease; Vitamin C may prevent this plaque formation by inhibiting the oxidative modification of low density lipoproteins (LDLs).

    Coenzyme Q10 is a coenzyme that is needed by every cell in the body to produce energy. It serves its energy enhancing function by acting in the portion of the cell known as the mitochondria, often referred to as the “powerhouse of the cell”. Here, it aids in the production of ATP, the most important form of energy needed to drive cell reactions and keeps the body running at peak capacity. It has antioxidant and immune enhancing properties and promotes healthy heart, brain, eyes, blood sugar level, and blood pressure.

    What does hydrolyzed marine collagen do?

    SKIN, HAIR AND NAILS. Collagen helps strengthens hair and nail follicles. It also contains two unique amino acids called hydroxyproline and hydroxylysine which are especially helpful for maintaining youthful, vibrant skin by smoothing fine lines and wrinkles and increasing the elasticity of the skin.

    JOINT HEALTH. Collagen supplementation helps decrease the size of the affected joint cavity, increases joint mobility, a decrease in pain from arthritis, joint and cartilage injuries. Collagen is essential for healthy bones, cartilage and other connective tissues. It also regenerates joints and cartilage, and improves joint flexibility.

    SPORTS PERFORMANCE. Marine collagen helps improve physical endurance and vitality. It is high in protein and contains numerous amino acids that are important for peak athletic performance. It helps reduce post-exercise stress after strenuous training. Marine collagen is also an excellent source of glycine, which allows the body to produce glycogen. Glycogen is a stored form of glucose which is used as an energy source in the muscles.

    Collagen Sea

    Collagen of Deep Sea Fish

    Molecular weight of common collagen is more than 300,000. These molecules of high molecular weight cannot be absorbed directly by the body. Collagen products must be broken down by digestive enzyme, i.e. protease into collagen peptide which has lower molecular weight to enable absorption by small intestines.

    Collagen of deep sea fish is a type of collagen with low molecular weight; furthermore its structure is similar to that of human beings, thus, collagen peptide from fish source can be absorbed most effectively by human body. In addition, it originates from pure uncontaminated deep sea, free from influences of animal diseases such as foot-and-mouth disease, bovine spongiform encephalopathy (BSE), mad cow disease, avian flu, etc.

    Vitamin C

    Synthesis of collagen needs Vitamin C, while collagen added with Vitamin C allows faster absorption by the body.

    The Essence of Bones and Skin

    The oral preparation of collagen will be hydrolyzed and absorbed in the gastrointestinal tract as raw material for the synthesis of collagen in the body. The greatest advantage of this preparation is self-absorption and self-synthesis without giving rise to adverse response.

    It produces significant effects which can last for a long period of time at affordable cost if compared to other methods, hence, can be accepted by more users who are concerned with their skin and bone health.

    Collagen Sea is 100% natural collagen food supplement capsules offering a convenient solution to a lifetime of rejuvenation—from head to toe. Each capsule of Collagen Sea provides Collagen (240 mg) and Vitamin C (10 mg). We recommend 3 capsules taken before bedtime. This is because our body is repairing while we are asleep and tissue is renewed. There are no reported side effects or contraindications when taking a medication.

    Collagen

    Collagen is the body’s major structural protein composed of three protein chains wound together in a tight triple helix. This unique structure gives collagen a greater tensile strength than steel. Approximately 33% of the protein in the body is collagen. This protein supports tissues and organs and connects these structures to bones. In fact, bones are also composed of collagen combined with certain minerals such as calcium and phosphorus.

    Collagen plays a key role in providing the structural scaffolding surrounding cells that helps to support cell shape and differentiation, similar to how steel rods reinforce a concrete block. The mesh-like collagen network binds cells together and provides the supportive framework or environment in which cells develop and function and tissues and bones heal.

    Collagen is a macromolecular protein that exists in skin, bones, teeth, tendons, etc. Physiologically, it acts as an adhesive substance for connecting tissues. Esthetically, it is a major ingredient to maintain elasticity of skin and muscles. When we exceed the age of 25, our skin starts to lose collagen with appearance of aging signs such as wrinkles, spots, etc. At this time, we need to replenish collagen for our skin. Apart from this, collagen is also a main element for healthy bones, nails and teeth.

    Collagen is a powerful long-term anti-aging solution, improving the skin’s elasticity and suppleness – visibly helping to reduce lines and wrinkles. Most people experience lots of welcome benefits by taking collagen including increased energy, relief from joint problems, overall toning, improved sleep and a greater overall sense of well-being.

    Collagen is a fibrous protein which is not only an essential constituent of health and young looking skin, but it is also the building block of tendons, bones and other connective tissues. Human joints are subjected to continuous wear and tear and in response, the body naturally works to rebuild the joint cartilage. To maintain this natural rebuilding function, the body requires sufficient quantities of collagen.

    Collagen and Beauty

    Collagen makes up 75% of our skin; thus, the smooth, plump appearance of young, healthy skin is due in large part to the presence of healthy collagens levels. Because of this, beauty seekers around the globe search for new ways to boost collagen levels and repair past collagen damage, some go so far as to inject collagen proteins into the skin to plump wrinkles and add volume to the lips. The breakdown of healthy collagen and the decline in collagen production lead to the development of unwanted wrinkles and the appearance of aged skin.

    Collagen Synthesis

    Collagen is created by fibroblasts, which are specialized skin cells located in the dermis. Fibroblasts also produce other skin structural proteins such as elastin (a protein which gives the skin its ability to snap back) and glucosaminoglycans (GAGs). GAGs make up the ground substance that keeps the dermis hydrated. In order to signal or turn on the production of skin structural proteins, fibroblast cells have specially shaped receptors on their outside membranes that act as binding sites to which signal molecules with a matching shape can fit. When the receptors are bound by the correct combination of signal molecule (called fibroblast growth factors, or FGFs), the fibroblast begins the production of collagen.

    Fibroblasts initially produce short collagen sub-units called procollagen. These are transported out of the fibroblast cells and later join together to form the complete collagen molecule. Vitamin C acts as a co-factor during many steps of the process. Without sufficient levels of Vitamin C, collagen formation is disrupted. This disruption leads to a variety of disorders such as scurvy – a disease where the body cannot produce collagen and as a result, essentially falls apart as these support structures (collagen) deteriorate.

    Collagen synthesis occurs continuously throughout our lives to repair and replace damaged collagen tissue or build new cellular structures. The degradation and recycling of old or damaged collagen is a healthy natural process used to create protein fragments needed to build new cellular structures, such as in the healing process. With age, collagen levels drop off due to decrease in production and an increase in degradation.

    Protecting Current Collagen Levels and Preventing Future Collagen Degradation

    The best way to maintain a healthy, youthful looking appearance is to protect the healthy collagen you currently have and to prevent future collagen degradation. These are two main ways to do this: 1) avoid UVA and UVB radiation and 2) prevent free radical damage.

    Exposure to ultraviolet (UVA and UVB) radiation emanating from the sun is the most prolific contributor to premature skin aging, accounting for an estimated 90 percent of the signs associated with aging skin. UV exposure must be limited and individuals should wear a daily sunscreen to protect healthy collagen. Many skin care companies understand this need and incorporate sunscreens into their daytime moisturizers. The second preventive step in protecting existing and future collagen levels is supplementation with both oral and topical antioxidants. As antioxidants fight free radicals from UV light, ozone, pollution, cigarette smoke and internal metabolic processes, they prevent the degradation of existing collagen fibers and protect the healthy function of fibroblast cells.

    Promoting the Synthesis of New Collagen

    There are many ways to promote the synthesis of new, healthy collagen. First, you can provide the skin with a reserve of Vitamin C. As a necessary co-factor in collagen synthesis, Vitamin C is proven to increase the production of collagen. One study showed that extended exposure of human connective tissue cells to Vitamin C stimulated an eight-fold increase in the synthesis of collagen (Murad et al, 1981).

    Another ways to promote the synthesis of collagen is to use chemical exfoliants, such as alphahydroxy acids, which break down the bonds between cells of the stratum corneum and slough away dead skin. Consistent exfoliation stimulates cell renewal. Chemical exfoliation has also been shown to increase dermal thickness. Scientists attribute this dermal thickening to the synthesis of glycosaminoglycans and collagen within the dermis.

    A third way to promote collagen synthesis is to supplement with collagen stimulating peptides. Fibroblasts are naturally stimulated to begin the synthesis of collagen when specific combinations of peptide signal molecules (fibroblast growth factors) bind to receptor sites on the fibroblast membrane. These signal molecules can be supplemented with topically and help boost collagen production. Some skin care companies are including these peptide fragments in their treatment products.

    Because collagen gives the skin its strength, durability and smooth, plump appearance, it is important to protect and promote collagen growth.

    Collagen in the Bones

    The same strong and abundant type I collagen found in the skin is also present in the bones. Type I collagen in the bones works with phosphorous salts and calcium to comprise the bone-building material. This combination attributes to 95% of the bone matrix. In addition to aiding cartilage and intervertebral cartilage, type XI collagen also contributes to bone enamel.

    Type I collagen continues to build up until about the age of 35, when the skin reaches the peak of its mechanical strength. After that Type I begin to decline as well.

    Human joints are subjected to continuous wear and tear and in response; the body naturally works to rebuild the joint cartilage. To maintain this natural rebuilding function the body requires sufficient quantities of collagen.

    Adoxy

    Oxygen Deficiency Symptoms
     
    Initial symptoms of oxygen deficiency may include overall weakness, fatigue, circulation problems, poor digestion, muscle aches and pains, dizziness, depression, memory loss, irrational behavior, irritability, acid stomach, and bronchial complications. When the immune system is compromised by a lack of oxygen, the body is more susceptible to opportunistic bacteria, viral, and parasitic infections and colds, as well as flu. Oxygen deprivation can also lead to life-threatening disease, such as cancer. Cancer, and most other infections or disease cannot live in an oxygen-rich environment. Dr. Otto Warburg, twice Nobel Laureate stated, “the primary cause of cancer is the replacement of normal oxygen respiration of body cells by anaerobic (i.e. oxygen deficient) cell respiration”. When scientists analyzed the oxygen content of air bubbles trapped in ice-core drillings at the Antarctica, they found that the earth’s atmosphere at one time contained between 38% and 44% oxygen. Over the years, increased pollution, increased toxins, mass rain forest destruction, and the reduction in of other natural oxygen producers have decreased the level of oxygen in our present day atmosphere from above 38% to below 20%. Because our bodies are not designed for low level oxygen consumption, harmful toxins accumulate in our cells, tissues, organs, and blood streams. For comparative purposes; a 6% oxygen level causes human asphyxiation and death. We can live for weeks without food... for days without water... but if you had stopped your oxygen intake from the time you first accessed this web site, you wouldn’t be reading this right now!

    Life with Oxygen

    Carbon, hydrogen, oxygen and hydrogen sulfur are essential minerals for our basic life. But the body of an element that we have the most is oxygen. We can live weeks without a meal. And live as many days without water. But if we lose air or oxygen only a few minutes, we can die because all of the body is controlled by oxygen. Ninety percent of the energy of life is based on the amount of oxygen.

    Oxygen stimulates cells to build up new energy. Our body requires oxygen to devour nutrients, eliminates waste and removing toxic substances. It uses as the media to create awareness in the process. The fact, a large number of oxygen leads to organs are able to work effectively. The body can think, sleep, eat and even speak distinctly. All but the total energy from oxygen.

    Oxygen is the only element types that are capable of combining with another element. Nearly all that combination will result in a compound are needed to build up and maintenance of the body organs such as the combining of oxygen with water, protein, carbohydrates, that will create a power of life. If without the oxygen, the body cannot work. And if it continues without the oxygen, we would probably not have the opportunity to experience what we call “life”!

    What is ADOXY and why is it so extraordinary?

    ADOXY is rapidly absorbed by the body to start the process of cleaning, building, regenerating and balancing the body as soon as you take it. It is safe, self-administered oxygen therapy treatment that provides oxygen and nutrients at the cellular level. It is the answer to CELLULAR OXYGEN DEFICIENCY and in INSTANT CELLULAR NOURISHMENT. It is composed of 17 amino acids, 34 enzymes & vitamins from plant sources, 78 ionic materials, dissolved oxygen, powerful antioxidants, electrolyte extracts form sea water & plant fossils, and deuterium-based product, which provides an unsurpassed oxygenating source and nutritional delivery system to every cell of the body. Its unique structure oxygenates and feeds the cells—CLEANING and TUNING UP our body systems all day long.

    ADOXY is capable of holding its components in a full aqueous solution and delivering them to every single cell. Its unique time-release delivery system ensures that nascent oxygen is created when ADOXY is mixed with water or juice, and that the vital nutrients are rapidly absorbed by the body at the cellular level. And ADOXY contains only the finest all-natural plant substances.

    ADOXY enables nascent oxygen to be generated by the splitting of water molecules in the body into atoms of nascent oxygen and hydrogen. Nascent means newly born; and, in biochemical terms, a newly born singlet atom of oxygen is negatively charged (O-). Free radicals (which many biochemists believe are the primary cause of the aging process and degenerative disease) are positively charged singlet atoms of oxygen (O+). The nascent oxygen atom (O-) is attracted to the (O+), forming a molecule of pure oxygen (O2) at cellular level where it is needed, for processes such as cleansing cells, e.g. combining with a single carbon atom to form carbon dioxide (CO2) which is expelled through the respiratory system.

    Where does ADOXY or CELL FOOD comes from?

    The genius and inventor behind Cell Food is Everett Storey, twice Nobel Laureate, who worked on the American “Manhattan Project”. This was a top-secret project; and, to this day, not much has been revealed about it. Albert Einstein credited Storey with the “water splitting technology” that he patented; and from his research, the hydrogen bomb was developed. Because of exposure to extreme radiation, the people on the project began to die. Everett Storey himself was affected and, by the early 1950s, he had lost 30 kg in weight. So, Storey worked on saving his own life and giving mankind something useful. In 1956, he invented a deuterium-based product, and he called “Cell Food” or “Liquid Life”. In the development of “Cell Food” Storey used the work of Dr. Harold Urey, who in 1932 had discovered deuterium (the only non-radioactive isotope of hydrogen), which had subsequently been kept secret because of its role in the hydrogen bomb and as the principal fuel for space exploration. Storey spent most of his life researching deuterium's incredible health benefits; this kept him alive until his death at the age of 74 in 1984. Directions for use in adults take 8 drops in 8 ounces of purified or distilled water, or juice, 3 times per day—or during stress or physical activity. It is best taken between meals (at least 15 minutes before or 1 hour after). May mix 1 day’s amount in water bottle and sip throughout day. Each 1-oz bottle of Cell Food contains 90 servings of 8 drops each, or 720 drops.

    Detoxification: Some may experience a cleansing or detoxification response. If so, halve dosage at beginning, and then gradually resume full dosage. Care when pouring. Use ADOXY carefully over any surfaces and materials when undiluted, as product contains organic enzymes. Avoid eye contact; rinse with water if dropped in eyes.

    About ADOXY

    Many health experts conclude that the lack of oxygen in human cells and tissue is linked to a vast variety of health problem and disease, and that supplemental oxygen therapies including ADOXY have remarkable physiological benefits.

    A diversity of beneficial oxygen therapies are being utilized today. Oxygen therapy is any process that safely increases the oxygen content in the body and should be administered by a licensed medical professional.

    ADOXY, however is a safe, self-administered oxygen therapy treatment that provides oxygen at the cellular level. This advanced, water splitting nano technology, is the answer to oxygen deficiency. Invented by Everett L. Storey, ADOXY is a super energized colloidal mineral concentrate. It contains 78 ionic minerals, 34 enzymes, 17 amino acids, electrolytes and dissolved oxygen-providing an oxygen and nutrient delivery system. All the substances in ADOXY are made from the finest natural substances. ADOXY has no alcohol, no glucose and is yeast free. Cryogenically (extreme cold) extracted, not chemically.

    ADOXY contains no substances that are on the banned list of substances regarding international, professional and amateur athletic associations.

    ADOXY’s unique structure oxygenates and feeds the cells-cleaning, and tuning up the body systems throughout the day.

    ADOXY is the most unique health drink in the world developed by Everett Storey, a man referred to as a genius by Albert Einstein because of his expertise in using deuterium to split the water molecules (H2O) into negatively charged oxygen atoms (O-), or “nascent oxygen” and positively charged hydrogen atoms (H+) or “nascent hydrogen”. In our body, the negatively charged oxygen atoms (O-) will bind with free radical oxygen (O+) produced by metabolism to form oxygen molecules (O- + O+ = O2) that are important to body cells in energy production. A certain amount of energy is needed for all metabolism transactions that determine the complete growth and functions of the body. Scientists are of the same opinion that energy deficit are the main cause to infections and diseases.

    Functions of ADOXY
      1. Destroys free radicals including those produced by radiation
    Free radicals are atoms (or groups of atoms) that are missing an electron. These highly reactive molecules become even more dangerous in the human body when they react with and damage other important cellular components like DNA. Antioxidants are directly responsible for the prevention of cellular damage by neutralizing and eliminating free radicals. Strengthens anti-oxidative function of body and inhibits harm of free radicals.
      2. Increases supply of oxygen; strengthens body cells; repairs and activate cells. Enhances activity of mitochondria, maintains integrity of cellular structure and delays aging.
      3. Balances body pH
    ADOXY Cell Food’s colloidal and ionic formula have a negative charge (as measure by Zeta potential testing). This negatively charged solution (like blood and lymph) allows for the rapid absorption and assimilation of nutrients. This process enables the body to more efficiently eliminate toxins and balance pH.
      4. Detoxification and promotes metabolism; Athletic performance enhancement
    ADOXY Cell Food is made from the finest all-natural, plant-based organic substances. It contains no alcohol, glucose, yeast, or gluten. It does not contain any ingredients that are on the “list of banned substances” for professional and amateur athletic competitions and associations. Adoxy Cell Food is non-addictive, non-invasive, and completely non-toxic.
      5. Enhances the immune systems
    Promotes metabolism of lipid and protein. Balances blood glucose.
      6. Healthy nerve functions
    Nourishes brain, improves memory, enhances cerebral function as well as delays aging and degeneration of brain. Increases physical strength and alleviates tiredness.
      7. Absorbs up to 95% nutrients and delivers nutrients to cells within 3 minutes.
      8. Improves skin texture, hasten wound healing and avoids tooth decay.
      9. Water treatment.
    10. Beneficial for plants and animals. ADOXY Cell Food provides nascent oxygen at the cellular level where it is needed.

    Health Benefits of Taking ADOXY:
    • Destroy free radicals
    • Increases supply of oxygen
    • Balances body pH
    • Detoxification and promotes metabolism of lipid and protein
    • Repairs and activate cells
    • Enhances the immune systems
    • Absorbs up to 95% of nutrients
    • Healthy nerve and cerebral functions
    • Improve skin texture, hasten wound healing
    • Balances blood glucose
    • Helps prevent tooth decay
    • Turns water molecules into nano size

    Oxygen Therapy—Comparison

    How important is oxygen to a healthy body? Many experts conclude that the lack of oxygen in human cells and tissue is linked to a vast variety of (and possibly all) health problems and diseases, and that supplemental oxygen therapies (including Cell Food) have remarkable physiological benefits. A diversity of beneficial oxygen therapies are being utilized today.

    What is oxygen therapy?

    Oxygen therapy is any supplemental process that safely increases the available dissolved oxygen content in the body. Therapies may also include processes that enhance the body's ability to use or promote oxygen absorption. Most treatments are generally expensive and should be administered or supervised by a licensed medical professional.

    Here are brief descriptions of some accepted oxygen therapies:
    • Bottled Oxygen – is often prescribed as inhalation therapy for serious bronchial and other respiratory problems.
    • Ozone Therapy (O3) – generally infused rectally or intravenously, is primarily used to increase blood oxygenation, circulation, immunity, and to kill bacteria, viruses and fungi. The ozone oxygen molecule is extremely unstable and can be toxic if not administered properly.
    • Hydrogen Peroxide Therapy (H2O2) – hydrogen peroxide is manufactured in the bloodstream to help fight bacteria, viruses, yeast, fungi, and other invading pathogens. The ingestion on H2O2 is extremely controversial because it can cause an adverse reaction in the digestive tract: excess hydrogen causes an unbalanced pH, as well as possibly produce dangerous free radicals. H2O2 therapy should only be utilized under the direct supervision of a licensed health care professional.
    • ADOXY Cell Food Therapy – the only safe, self-administered, oxygen therapy treatment not requiring a medical prescription and provides bioavailability oxygen at the cellular level. This advanced technology is the answer to oxygen deficiency.

    Frequently Asked Questions

      1. Is ADOXY a medicine?
    No. ADOXY is not a medicine. ADOXY is currently classified as a nutritional supplement.

      2. What is the shelf life of ADOXY?
    The shelf life is indefinite. Recent testing of 25-year old samples have demonstrated an improvement in potency.

      3. How does the body absorb ADOXY?
    The nutrients in ADOXY are in colloidal form. Colloidal particles are minute (4-7 nanometers in diameter), and because of the Brownian Movement Phenomenon, they take on a negative charge and remain suspended in liquid. Because most bodily fluids are colloidal and negatively charged; the body perceives ADOXY as normal healthy body fluid and allows the nutrients to pass immediately through the sensitive membranes of the mouth, throat, and esophagus, directly in the blood stream.

      4. How is ADOXY different from other so-called oxygen products?
    Other so-called oxygen products tend to flood the body with oxygen, often creating dangerous oxygen free radicals. “The release of these reactive oxygen species results in oxidative injury to biologic systems such as lipids found in cell membranes and proteins found in blood vessels and myocardial tissues.” Adoxy actually bonds with dangerous oxygen free radicals supplying the body with usable pure oxygen in a time release manner, directly to the cells.

      5. How do I take ADOXY?
    ADOXY is a liquid concentrate, taken orally by mixing a number of drops (see individual label for instructions) in water. If you use ordinary tap water, ADOXY begins purifying the water and the benefit you receive from ADOXY is reduced. ADOXY has a slightly sour lemon taste. Should you find this unpleasant, you can use more water or mix ADOXY with a fruit juice.

      6. Can I overdose on ADOXY?
    No, ADOXY is a nutritional supplement made from natural substances. The body only uses what it needs, and eliminates the rest through the normal channels of elimination. What happens if I get no results? Sometimes a person is unaware of the “work” that ADOXY is facilitating at deep cellular levels. People who first reported “no results” from taking ADOXY later reported, after physical examinations, that their cholesterol and blood pressure levels had dropped significantly. These are similar accounts regarding the normalization of uric acid and blood sugar levels. Additionally, ADOXY is designed to raise the frequencies of all organs, making them more resistant to the lower frequencies of viruses, bacteria, and parasites. This fortification of the immune system helps the body became more capable of combating microorganisms that could be detrimental to the general health.

      7. Am I “cheating” if I use ADOXY during sports competitions?
    No, ADOXY is made from the finest natural ingredients, none of which are on the “list of banned substances” issued and governed by international, professional, and amateur athletic associations.

      8. What if I am already taking medicine?
    ADOXY can be used in conjunction with other nutritional supplements or medicines because it increases the bioavailability of these other substances enabling the body to more effectively use them. Many Adoxy users have reported within a few weeks or months of continual use, a gradual decrease in need for medication. If you are pregnant of under medical care, please consult your medical practitioner before using.